Understandings:
3.4.U1: Mendel discovered the principles of inheritance with experiments in which large numbers of pea plants were crossed
3.4.U2: Gametes are haploid so contain only one allele of each gene
3.4.U3 The alleles of each gene separate into different haploid daughter nuclei during meiosis.
3.4.U4: Fusion of gametes results in diploid zygotes with two alleles of each gene that may be the same allele or different alleles
3.4.U5: Dominant alleles mask the effect of recessive alleles but co-dominant alleles have joint effects
3.4.U6 Many genetic diseases in human are due to recessive alleles of autosomal genes.
3.4.U7 Some genetic diseases are sex-linked and some are due to dominant or co-dominant alleles.
3.4.U8: The pattern of inheritance is different with sex-linked genes due to their location on sex chromosomes
3.4.U9: Many genetic diseases have been identified in humans but most are very rare
3.4.U10: Radiation and mutagenic chemicals increase the mutation rate and can cause genetic diseases and cancer
Applications:
3.4.A1: Inheritance of ABO blood groups
3.4.A2: Red-green colour blindness and haemophilia as examples of sex-linked inheritance
3.4.A3: Inheritance of cystic fibrosis and Huntington’s disease
3.4.A4: Consequences of radiation after nuclear bombing of Hiroshima and accident at Chernobyl
Skill:
3.4.S1: Construction of Punnett grids for predicting the outcomes of monohybrid genetic crosses
3.4.S2: Comparison of predicted and actual outcomes of genetic crosses using real data
3.4.S3: Analysis of pedigree charts to deduce the patterns of inheritance of genetic diseases
Nature of Science:
3.4.NOS Making quantitative measurements with replicates to ensure reliability, Mendel’s genetic crosses with peas plants generated numerical data.
3.4.U1: Mendel discovered the principles of inheritance with experiments in which large numbers of pea plants were crossed
3.4.U2: Gametes are haploid so contain only one allele of each gene
3.4.U3 The alleles of each gene separate into different haploid daughter nuclei during meiosis.
3.4.U4: Fusion of gametes results in diploid zygotes with two alleles of each gene that may be the same allele or different alleles
3.4.U5: Dominant alleles mask the effect of recessive alleles but co-dominant alleles have joint effects
3.4.U6 Many genetic diseases in human are due to recessive alleles of autosomal genes.
3.4.U7 Some genetic diseases are sex-linked and some are due to dominant or co-dominant alleles.
3.4.U8: The pattern of inheritance is different with sex-linked genes due to their location on sex chromosomes
3.4.U9: Many genetic diseases have been identified in humans but most are very rare
3.4.U10: Radiation and mutagenic chemicals increase the mutation rate and can cause genetic diseases and cancer
Applications:
3.4.A1: Inheritance of ABO blood groups
3.4.A2: Red-green colour blindness and haemophilia as examples of sex-linked inheritance
3.4.A3: Inheritance of cystic fibrosis and Huntington’s disease
3.4.A4: Consequences of radiation after nuclear bombing of Hiroshima and accident at Chernobyl
Skill:
3.4.S1: Construction of Punnett grids for predicting the outcomes of monohybrid genetic crosses
3.4.S2: Comparison of predicted and actual outcomes of genetic crosses using real data
3.4.S3: Analysis of pedigree charts to deduce the patterns of inheritance of genetic diseases
Nature of Science:
3.4.NOS Making quantitative measurements with replicates to ensure reliability, Mendel’s genetic crosses with peas plants generated numerical data.